Fungal inhabitants in lichen thali are particularly referred as Endolichenic Fungi (ELF). These fungi are rich in novel unexplored metabolites and the aim of the present study was to isolate characterize such metabolites. Two pure compounds, 1 and 2 were isolated and the structures were identied. Compound 1 did not show any radical scavenging activity in DPPH assay. Compound 2, identied as 8-methoxynaphthalen-1-ol showed strong radical scavenging ability in the DPPH assay with a half maximal inhibitory concentration (IC50) of 10.2 ± 5.8 μg/ mL. The activity of compound 2 was higher than that of the standard, butylated hydroxy toluene (BHT). 

M. A. T. P. Manthrirathna, R. Kandiah, D. S. Gunasekera, K. A. U. Samanthi, D. T. Welideniya, H. A. K. Maduranga, P. A. Paranagama

Journal of the National Science Foundation of Sri Lanka

Abstract :- http://doi.org/10.4038/jnsfsr.v48i2.10095