Assessment of Developmental and Reproductive Fitness of Dengue-Resistant Transgenic Aedes aegypti and Improvement of Fitness Using Antibiotics

 

Development of a dengue vector mosquito blocking transmission of dengue viruses is important for integrated control of dengue vector mosquitoes. Assessment of developmental and reproductive fitness of a dengue-resistant transgenic Aedes aegypti with respect to its wild mosquitoes were assessed. Transgenic mosquito showed reduction of the fitness parameters and it may lead to a subsequent reduction of transgenic vector density over the generations in field applications. However, antibiotics of co-trimoxazole, amoxicillin, and doxycycline have shown the improvement of fitness parameters indicating the usefulness in field release of transgenic mosquitoes. 

 

H.P.B.K.D. Ramyasoma, R.S. Dassanayake, M. Hapugoda, and Y.I.N.S. Gunawardene

BioMed Research International

Abstract :- https://doi.org/10.1155/2021/6649038

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