Fungal inhabitants in lichen thali are particularly referred as Endolichenic Fungi (ELF). These fungi are rich in novel unexplored metabolites and the aim of the present study was to isolate characterize such metabolites. We found a novel bioactive compounds named Neurosporalol 1 and 2 from an Endolichenic Fungus Neurospora ugadawe Inhabited in a Lichen Host from Mangrove Ecosystem in Puttalam lagoon in Sri Lanka. Neurosporalol 1 showed the highest antioxidant activity and Neurosporalol 2 showed comparable antioxidant and moderate anti-inflammatory activities. 

  H.A.K. Maduranga, W.R.H. Weerasinghe, R.N. Attanayake, S. Santhirasegaram, C.D. Shevkar, A.S. Kate, G. Weerakoon, K.A.U. Samanthi, K. Kalia and P. A. Paranagama

Asian Journal Of Chemistry

Abstract :- https://doi.org/10.14233/ajchem.2021.23229